Inoperable Options

Radiosurgery

Brain tumours less than 4 cm in diameter may be eligible for stereotactic radiosurgery using Gamma knife. Gamma knife is a procedure in which 201 sources of Cobalt-60, emitting gamma ray photons, allow for precision targeting of tumour tissue through the skull, without surgery. The treatment typically takes 10-60 minutes and is performed on an outpatient basis in a single sitting. Find Gamma Knife treatment centers worldwide at the elekta.com website. Dozens of Gamma Knife treatment centers are located across the USA and three centers are operational in Canada (Winnipeg, Toronto, and Sherbrooke Quebec).

Laser Interstitial Thermal Therapy (NeuroBlate)

Another potential option for “inoperable” tumours is the NeuroBlate system which uses lasers directed through a laser probe inserted into the tumour, killing tumour cells with heat. This therapy is also known as laser interstitial thermal therapy (LITT). The Cleveland Clinic in Ohio is one centre using this technology for brain tumors. Brain surgeons using the NeuroBlate technology are currently located in Cleveland OH, Philadelphia PA, New Haven CT, Richmond VA, Dayton OH, Winston-Salem NC, Charlotte NC, St Louis MO, Rochester MN, Atlanta GA, Jacksonville FL, Winter Park FL, Orlando FL, Kansas City MO, Kansas City KS, Dallas TX, Houston TX, San Antonio TX, San Diego CA, and Vancouver BC (Canada). Find location closest to you at this webpage.

MRI-Guided Focused ultrasound

MRI-guided focused ultrasound therapy is generally being tested for brain tumours that are internally located and inaccessible to surgical resection.

ExAblate (Magnetic Resonance-guided Focused Ultrasound Surgery) Treatment of Brain Tumors. A safety and feasibility study. Toronto, Canada. Estimated primary completion date: December 2015. Recurrent or progressive tumours only. This treatment will be offered as an option for those patients where neither surgery or repeat radiotherapy is advised by the multidisciplinary team. The targeted tumor tissue is located in the cerebral hemispheres, > 2.5 cm from the inner table of the skull. Last updated March 2015.
NCT01473485